Can I keep doing vigorous sessions late in pregnancy?
In low-risk pregnancies (12 studies, 8,006 babies), vigorous work into the third trimester showed no difference in birth weight (+8 g, −57 to 74) or small babies. Mostly <90% HRmax.
Beetham and colleagues asked whether vigorous exercise during pregnancy, and in particular in the third trimester, when fetal demands are highest, harms the infant or the mother.
They searched six databases to November 2018 for RCTs, quasi-experimental, cohort and case-control studies in which pregnant women did vigorous exercise against lower-intensity exercise or standard care, and reviewed each study's methods against the Exercise and Sports Science Australia intensity terms (vigorous: at least 70% of maximum heart rate, or unable to hold a conversation; high intensity: 90% or more).
Fifteen studies were included: 5 RCTs (623 women) and 10 observational studies (32,080), of which 13 went into random-effects multi-level meta-analyses. Planned trimester comparisons were not possible: the data allowed only exercise continued into the third trimester.
Birth weight did not differ between infants of women who did and did not exercise vigorously (mean difference 8.06 g, 95% CI −57.44 to 73.55, 12 studies, 8,006 infants), with no difference by study design or comparison group.
Small-for-gestational-age and low birth weight showed no significant increase, maternal weight gain did not differ (−0.46 kg, −2.05 to 1.12), gestation was 0.21 weeks longer (0.15 to 0.27; 39+4 vs 39+3 weeks) and prematurity was slightly lower. The RCTs reported no excess adverse events, but their programmes started late in the first trimester or in the second.
Most studies stayed below 90% of maximum heart rate; the authors conclude that vigorous exercise into the third trimester "appears to be safe for most healthy pregnancies", and advise women to avoid exertion relative to 90% of maximum heart rate or more until research confirms its safety.
Our reading: this is the base's pooled answer for vigorous work late in pregnancy in the general population, reassuring on growth and gestation; the ratios reported as risk ratios are log risk ratios (the forest plots are labelled so), which turns the small-for-gestational-age estimate into about 1.16 (0.94 to 1.42) and the prematurity estimate into about 0.82 (0.70 to 0.97) on the usual scale (our arithmetic); and the advice to stay under 90% is a precaution resting on a 6-athlete study (REF-1400), not a tested limit.
Protocol
Key Results
| Outcome, vigorous exercise into the third trimester vs control | Studies (infants or women) | As printed (95% CI) | On the usual ratio scale (our arithmetic) |
|---|---|---|---|
| Birth weight | 12 (8,006) | +8.06 g (−57.44 to 73.55), p = 0.79, I² 53.92 [0, 85.03] | — |
| Small for gestational age | 7 (4,504) | RR as printed 0.15 (−0.06 to 0.35), p = 0.13 | RR about 1.16 (0.94 to 1.42) |
| Low birth weight (<2500 g) | 4 (2,454) | RR as printed 0.44 (−0.83 to 1.7), p = 0.35 | RR about 1.55 (0.44 to 5.47) |
| Gestational age at delivery | 7 (4,281) | +0.21 weeks (0.15 to 0.27), p < 0.001; 39+4 vs 39+3 weeks | about 1.5 days |
| Prematurity | 4 (3,025) | RR as printed −0.20 (−0.36 to −0.03), p = 0.03 | RR about 0.82 (0.70 to 0.97) |
| Prematurity, the two RCTs only | 2 (312) | RR as printed −0.41 (−1.64 to 0.82) | RR about 0.66 (0.19 to 2.27) |
| Maternal weight gain | 7 (1,834) | −0.46 kg (−2.05 to 1.12), p = 0.5, I² 68.94 [0, 95.2] | — |
Mechanisms
Practical Application
Limitations
How this entry was checked and changed
a registered systematic review with meta-analysis; held below A because most pooled women come from observational studies (8 cohort or case-control studies vs 5 RCTs with 623 women), vigorous intensity was defined inconsistently across studies and re-classified by the reviewers, the confidence intervals of I² are very wide (e.g. 0 to 85.03 for birth weight), no GRADE or other certainty rating was made, and the ratios are reported on the log scale while labelled risk ratios. Read from the full text (Europe PMC, CC BY 4.0); the three additional files (search terms, intensity definitions, moderation tables) not read