REF-1708 · Río et al., 2026 · Gait & Posture, · Paper · PubMed

Switching to minimalist shoes went with more injuries in runners new to them: a meta-analysis of 7 trials and prospective cohorts (313 healthy runners, transitions of at least 4 weeks) reports a pooled effect of 3.529 (95% CI 2.41-4.646, low heterogeneity) that the authors call a moderate increase in injury risk, without naming the effect measure; the most reported problems were bone marrow oedema in the metatarsals, Achilles tendinopathy and calf pain, which the authors tie to adopting a forefoot strike

Main caveat: Effect measure not named: "3.529 (2.41-4.646)" cannot be read as a risk ratio, odds ratio or prevalence without the full text, and the comparator is not stated.
moderate evidenceMeasured on non-athletes to trained athletesRead from the abstract only

Río and colleagues asked how often runners get injured when they move to minimalist footwear, and which biomechanical and musculoskeletal changes go with that risk. They searched international databases covering the previous 15 years for randomised trials and prospective cohorts in healthy runners with no minimalist experience who transitioned for at least four weeks.

Twelve studies entered the qualitative synthesis and seven, with 313 participants, the fixed-effect meta-analysis. The transition was associated with what the authors call a moderate increase in injury risk (overall effect 3.529, 95% CI 2.41-4.646) with low heterogeneity.

The injuries reported most often were bone marrow oedema in the metatarsals, Achilles tendinopathy and calf pain, which the authors relate to a change to a forefoot strike.

They conclude that the transition raises injury risk and the prevalence of musculoskeletal injury through changed foot strike and overload of the forefoot and Achilles tendon, and that supervised retraining of at least 12 weeks may support adaptation and reduce risk.

Our reading: the direction is clear, but the size cannot be read, because the abstract does not say whether 3.529 is a risk ratio, an odds ratio or another measure, and its interval is symmetric on the linear scale, which is unusual for a ratio (our arithmetic: 3.529 − 2.41 = 1.119; 4.646 − 3.529 = 1.117).

Participants

7 studies, 313 participants in the meta-analysis; 12 studies in the qualitative synthesis.
Healthy runners with no previous minimalist-footwear experience; age, sex, weekly volume and running level are not in the abstract.

Protocol

Search: international databases, the last 15 years (databases and end date not named in the abstract); PRISMA 2020.
Inclusion: randomised controlled trials and prospective cohort studies; a transition to minimalist footwear of at least 4 weeks; healthy runners new to minimalist shoes.
Analysis: fixed-effect model; Cochran's Q and I².
Not in the abstract: the effect measure, the comparator, how injury was defined and diagnosed, the risk-of-bias tool and its results, the transition protocols, registration and funding.

Key Results

OutcomeStudies, nResult
Injury with a transition to minimalist footwear7, 313Overall effect 3.529 (95% CI 2.41-4.646), low heterogeneity; measure not named; the authors call it a moderate increase in risk
Most frequently reported injuriesqualitative synthesis (12 studies)Metatarsal bone marrow oedema, Achilles tendinopathy, calf pain, linked by the authors to adopting a forefoot strike
The I² value, injury counts and the split between imaging findings and clinical injuries are not in the abstract.

Practical Application

A switch to minimalist shoes carries an injury cost; do it slowly or not at all. Across 7 trials and cohorts (313 runners new to the shoes) the transition went with more injuries, mostly metatarsal bone marrow oedema, Achilles tendinopathy and calf pain; how much more cannot be read from the abstract, which does not name its effect measure.
Consistent with [SYNTH-86] and [SYNTH-94]: SYNTH-86 leaves a pain-free runner's landing alone and says a switch to minimal shoes takes months, not weeks, and SYNTH-94 does not recommend shoes for prevention and counts the 10-week minimalist switch's marrow oedema as a marker, not an injury (REF-715).This review pools that kind of study and points the same way; it changes neither guide's default, and its forefoot-strike link fits SYNTH-86's point that a forefoot strike moves load to the ankle and Achilles (REF-1113).
The authors' 12-week figure is their suggestion, not a tested programme: the abstract does not report a comparison of transition lengths or of supervised against unsupervised retraining. The base's timing for a switch stays practice (SYNTH-86).
Not treatment advice: pain at one spot on a metatarsal or the top of the foot, or Achilles pain that builds through runs, means no running through it and a physiotherapist or physician, who decides (SYNTH-94).

Limitations

Effect measure not named: "3.529 (2.41-4.646)" cannot be read as a risk ratio, odds ratio or prevalence without the full text, and the comparator is not stated.
Imaging and clinical injury mixed: metatarsal bone marrow oedema is an MRI finding; whether it was counted as an injury in the pooled effect is not in the abstract.
Fixed-effect model on a mix of randomised trials and cohorts; the low heterogeneity is stated without a value.
Small evidence base: 7 studies, 313 runners.
The 12-week recommendation is the authors' conclusion; no tested comparison is reported in the abstract.
Not in the abstract: databases and dates, risk of bias, transition protocols, participant characteristics, funding.
Written from the abstract and the PubMed record; full text not read.
How this entry was checked and changed
Why this level

risk of bias not read (abstract only); the abstract also does not name the pooled effect measure or the comparison (conventional shoes or the runners' own baseline), and the most reported "injury", metatarsal bone marrow oedema, is an imaging finding, but the pooled outcome is injury and how much of it rests on imaging is unknown, so the marker step (rule 3) is not applied