SYNTH-68 · Guide

Drinking and sodium

Drink to thirst by default, plan drinking only in the heat when the effort is hard or over ~60 min, and never beyond your measured sweat loss, treat finishing heavier as the warning, and fit sodium to the fluid you actually replace; salt prevents neither hyponatraemia in someone who overdrinks nor most cramps

Blimited evidenceMostly from recreational to elite athletesWritten before October 2026, being re-checked

The question it answers

How much should this athlete drink in training and in a race, does salt matter for them, how do they find their own sweat rate, and how do they avoid both a performance-costing deficit and dangerous overdrinking?

Default (what to prescribe first)

1

Drink to thirst. Using thirst to guide drinking should limit overdrinking while still preventing excessive dehydration, and the cues persist in hot and cold conditions (REF-776, A-, consensus, Grade 1C). The ultramarathon nutrition review says euhydration can generally be maintained by drinking to thirst (REF-663, B+, narrative review).

2

Never drink more than you lose. EAH, and all known deaths from it, come from drinking hypotonic fluid (water or sports drink) beyond what is lost, likely with non-osmotic antidiuretic hormone secretion (REF-776, Grade 1A). Almost all symptomatic cases gained or held body weight when some loss was expected (REF-776).

3

In the heat, keep the net deficit under about 2% of body mass. The UCI statement sets <2%, especially in heat, with strategies from ad libitum to a plan built on measured sweat rates (REF-748, A, cycling, written for professional riders). Losses >2% usually impair aerobic performance in warm-hot conditions, sometimes in temperate ones and not in the cold (REF-062, B+, narrative review).

4

Sodium follows fluid. There is no evidence athletes need more dietary sodium day to day, and sodium around exercise should be planned against how much is drunk and lost, not sweat sodium alone (REF-220, B+, narrative review).

5

Weigh yourself before and after representative sessions to learn your sweat rate: body-mass change, corrected for what was drunk, passed and trapped in clothing, is the simplest and most accurate whole-body method (REF-916, B+, methods review). The session details below are the base's own practice.

Decision — who → what

SituationDrink and sodium (volumes and cut-offs are practice unless a refId carries them)Source and how sure
Short session, under ~60-90 min, cool or temperateThirst; water is fine; no sodium target; start euhydratedAn editorial says thirst may suffice for low-to-moderate exercise <60 min in cool climates (REF-225, C). >2% loss did not impair submaximal aerobic performance in cold-cool conditions (REF-062, B+). The 60-90 min line is practice
1-3 h trainingThirst-led with a bottle always available; a hypotonic carbohydrate-electrolyte drink during the ride; sodium to tasteHypotonic drinks held plasma volume best over 0-180 min of exercise (−6.3% vs isotonic −8.7%, water −7.5%) (REF-224, A, 28 studies; a surrogate, no performance outcome). A model found sodium replacement unnecessary for a soccer match or an elite marathon in every realistic scenario (REF-223, C, no participants). SYNTH-02's 500-800 mL/h is its own practice; inference: never above the athlete's weighed loss
Hot race or key session over ~60 minPlan bottles per hour from a weighed sweat rate so the deficit stays under ~2%, and never above 100% of the loss; heat-acclimate first; pre-coolPlanned drinking favoured in heat for high intensity and >60 min, because thirst may appear only after ~1.5 L is lost (REF-225, C, editorial). ~2.4% hypohydration cut 15-min cycling work 165 → 152 kJ at 34 °C (REF-226, B, 7 active men, blinded). Consensus order: acclimatization, then euhydration, then cooling (REF-061, A); protocol SYNTH-04
Hot race: pre-start sodiumOptional; rehearse first~757 mL of a 164 mmol/L sodium drink (≈2.9 g) finished 45 min before a run at 32 °C raised plasma volume 4.5% and time to exhaustion 75 → 96 min in those who ran to exhaustion (REF-007, B, 8 trained male runners; running and an exhaustion test, transfer to a cycling race is inference)
Marathon, Ironman, ultraThirst, not a schedule (in the heat the hot-race row above applies: a plan from a weighed sweat rate, never above the loss, with thirst overriding it downward); weigh before and after; finishing heavier, or not lighter, is the warning. Sodium in drinks is fine, but it is not a licence to drink moreSports drinks (about 10-38 mmol/L sodium) are far below blood (~140 mmol/L), so they cannot prevent EAH when intake stays excessive (REF-776, Grade 1C). Body-weight loss under 0.75 kg after a standard marathon went with asymptomatic EAH (REF-776). Among 488 Boston Marathon finishers, 13 percent were hyponatraemic and 0.6 percent critically; weight gain (odds ratio 4.2) and a finish over 4:00 hours vs under 3:30 (odds ratio 7.4) were independent risk factors, and the composition of fluids was not (REF-915, B+, one race, observational)
Who is at risk of EAHAnyone whose intake stays above sweat, respiratory and urine losses; long events; the severe cases mostly recreational. Warn slower finishers and those at body-mass-index extremesREF-776. In one marathon cohort, after adjustment: weight gain, a finish over 4:00 hours and body-mass-index extremes; female sex, fluid composition and NSAID use were not associated (REF-915, B+). Inference: a slower athlete spends more hours near fluid, so a fixed mL/h plan adds up to more water
Salty sweater (white residue, stinging sweat — practice cues, not validated)Sodium to taste in training; a sweat-sodium test earns its cost only for very long events where the athlete plans to drink back most lossesSweat sodium: only 17-23% of its variation explained by the measured factors; sodium intake, humidity and duration explained none (REF-222, B+, 1,944 tests). Targeted sodium needed only in a 160 km ultra with sweat sodium ≥40 mmol/L and >80% of losses replaced (REF-223, C, model, running). A sweat-sodium result depends on collection site, timing, skin cleaning, storage and analysis — ask how it was obtained (REF-916, B+)
Cramp-prone athleteDo not prescribe salt or extra fluid as the fix; stop, stretch gently until it releases, ride or run on easier; then (practice) work on pacing, conditioning for race demands, and heatDehydration and electrolyte explanations rest on anecdote, 18 case reports and one case-control study of 10, and four prospective cohorts do not support them (REF-232, B+). Risk factors: cramp history, fatigue, heat and humidity, novel or harder exercise; sweat losses a minor contributor for most; magnesium no meaningful benefit (REF-233, B+)
Masters athleteIn heat, plan drinking rather than relying on thirst alone, still capped by weighed lossUCI: thirst and sweat capacity decline, so hydration in heat needs a plan (REF-748, A, a position statement line; no primary masters hydration study in the base). This departs from REF-776's thirst rule; the cap at measured loss is the base's reconciliation (inference)
WomanNo separate volume ruleWomen sweated less than men only at the highest heat-loss requirement (REF-712, B, 8 + 8, cycling); sweat rate did not differ by cycle phase (REF-709, B+); in Boston, female sex went with EAH only before adjustment (REF-915). Inference: lower sweat loss means a fixed plan overshoots sooner

The ultra conflict, stated. The ISSN ultra stand gives 450-750 mL/h (~150-250 mL every 20 min), rising in heat, and says sodium may be needed above what most commercial products provide (>575 mg/L) (REF-528, A, running).

The hyponatraemia consensus says drink to thirst and that sodium does not protect someone who overdrinks (REF-776, A-), and the ultra review agrees on thirst (REF-663, B+).

The base's resolution (inference, not tested): use the stand's range only as a planning ceiling for athletes whose weighed sweat rate is at or above it, never as a floor to drink to; thirst overrides the schedule downward.

One world-class mountain runner drank 0.87 L/h on average (1 L/h with about 1.5 g of sodium per litre after the first 4 h) in a 100-mile race at up to 40 °C and still finished 4.3% lighter (REF-1194, C+, case study), above the ~2% heat limit in this framework's default; the authors wrote that higher intakes "would be required" but may not be practical, and part of the mass lost over 14 h is fuel oxidised, not water (inference).

An observation, not a test of either rule.

The sweat-rate test (house protocol)

The method — body-mass change corrected for non-sweat mass changes and sweat trapped in clothing — is the simplest and most accurate for whole-body sweat rate (REF-916, B+).

The session details are the base's own practice: after voiding, weigh nude and towel-dried; do a representative session of ≥60 min at race intensity and in race-like conditions; weigh again nude and dried. Sweat loss (L) ≈ mass before − mass after (kg) + fluid drunk (L) − any urine passed; divide by hours. Mass change ÷ start mass × 100 is the % deficit.

Starting estimate without a test: endurance athletes averaged 1.28 ± 0.57 L/h and lost 51.7 ± 27.8 mmol sodium per hour (REF-221, B+, 1,303 athletes) — a population mean, not an individual value.
Indoor estimate: a cycle-ergometer prediction model had a mean absolute error of 0.01 L/h (95% CI +0.25/−0.22 L/h) across 20-40 °C in independent validation (REF-231, B, indoor only; outdoor use is inference).
Test in the season you race in: sweat sodium was lower in warmer months, a proxy for acclimatization (REF-222, B+, association); intensity, environment, heat acclimation, diet and hydration all shift sweat rate and sodium, so one test is a snapshot (REF-916).
Airflow changes the need: with ~33 km/h of facing airflow, replacing 80.0% rather than 58.8% of sweat loss changed neither heat storage nor body temperature (REF-886, B, 9 subjects, 2 h at 33 °C). Inference: outdoors, drinking back well under 100% is usually enough; an indoor trainer without a fan is close to still air.

Before and after

Before: start euhydrated (REF-061, A; REF-748, A). In a 1,230 km ride riders started with urine specific gravity 1.022, which the authors call suboptimal (REF-799, B, 14 riders). Not from a study; the base's own practice: a normal pre-race meal with fluid, pale urine at the start; no large volumes of plain water in the final hours, because excess water before the start adds to the positive balance REF-776 describes (inference).
After: after a >2% deficit, fluid at 125-150% of the loss over 4-6 h with sodium (~50-80 mmol/L or salted food) (REF-748, A). After 60 min of cycling (1.36% deficit) and 150% of the loss, coconut water and a sports drink each produced 170 mL urine vs 530 mL with flavored water, with final fluid status not significantly different (REF-230, B, 8 recreational athletes).Milk and an oral rehydration solution retained ~50% more fluid at 2 h than water (REF-058, B+, 72 rested euhydrated men — transfer to post-exercise is inference).

How to progress / periodise

Not from a study; the base's own practice: do one sweat test in base training and one in the hot months; rehearse the race drinking and fuelling in long sessions, as the ultra stand's individualised framing asks (REF-528); retest after heat acclimation (SYNTH-04) because sweat sodium tracked season (REF-222). Settle the plan before race day: riders told they were 2% dehydrated when actually ~1.5% down did 5.6 ± 6.1% less work (REF-227, B, 9 active men, heat).

When NOT to use it / red flags

Weight gain or no weight loss over a long event is the EAH warning (REF-776; weight gain odds ratio 4.2 in REF-915); the fix is to stop drinking (inference from REF-776: fluids are withheld until urination, and sodium cannot offset continued overdrinking).
Symptoms: EAH runs from mild non-specific complaints to severe encephalopathy, and severity, not the sodium number, guides treatment (REF-776, Grade 1A). Not from the paper's wording; the base's own practice: a worsening headache, nausea or vomiting, confusion or unusual drowsiness after drinking a lot = medical help now and no more water or sports drink until assessed.In a hyponatraemic athlete, hypotonic or isotonic fluids are withheld until urination (REF-776, Grade 1C); suspected severe EAH is treated by medical staff with intravenous hypertonic saline without waiting for a lab value (Grade 1B).
Do not diagnose dehydration from heart-rate drift: with sweat losses fully replaced, HR still drifted 11% at 35 °C vs 2% at 22 °C (REF-3496, B+, 10 trained men).

What the evidence does and does not show

Shows: overdrinking causes EAH and thirst is the consensus prevention (REF-776); >2% loss hurts in the heat, not the cold (REF-062, REF-226); the physiological strain of a deficit grows with exercise intensity (REF-228, B+, narrative review, not a performance trial); sodium needs track fluid replaced and sweat sodium (REF-223, REF-220); one narrative review names altered neuromuscular control as the principal cramp mechanism while asking for more evidence (REF-232), and a later one calls the cause still controversial (REF-233).
Does not show: a validated mL/h figure for an individual; thirst versus planned drinking head to head on race performance; how much of the prevention advice applies to women, masters or beginners; any trial in which sodium supplements prevented cramps or EAH.

Evidence gaps

EAH risk factors beyond one marathon cohort (REF-915, 2002 Boston, self-reported intake); no entry in triathlon or ultra fields.
Ageing and thirst — only a UCI statement line; candidate: Kenney & Chiu 2001, Med Sci Sports Exerc (not in the base).
Patch vs whole-body sweat-sodium agreement in numbers — REF-916 names the sources of error without values.
Sodium supplementation and EAH or cramps in ultra field studies — candidate: Hoffman & Stuempfle 2015 (not in the base).
Meta-analysis of dehydration and time-trial performance with ad libitum drinking — candidate: Goulet 2011, Br J Sports Med (not in the base).
Glycerol hyperhydration protocols, caffeine and alcohol fluid effects, cold-weather drinking — no entries.
How this entry was checked and changed
Why this level

(the safety rule rests on an A- consensus whose recommendations are mostly graded 1C and a B+ Boston Marathon cohort; the weigh-in method on a B+ methods review; the heat-performance threshold on a B+ review, an A cycling position statement and two small B crossovers in active men; sodium on a B+ review and a C model with no participants; drinking volumes, the sweat-test session details and the hour cut-offs are house practice)

Content correction 2026-09-27
Revision 2026-09-30: folded in REF-915 (Almond 2005, B+, 488 Boston finishers): weight gain (OR 4.2) and a finish over 4:00 h (OR 7.4) now carry the 'finishing heavier is the warning' line and the marathon row with a refId; the 'who is at risk' row no longer says slower pace and body size are unstated (BMI extremes independent; female sex and NSAIDs not associated after adjustment). Gap narrowed.
Revision 2026-09-30: folded in REF-916 (Baker 2017, B+ methods review): the weigh-in sweat-rate method is no longer labelled practice (the session details — nude, ≥60 min, race-like — stay practice); sweat-sodium test caveat added to the salty-sweater row; season-testing line extended. Level line updated; level unchanged (B). Default unchanged.
Verification 2026-10-01: all 29 cited REF entries read in the KB.md snapshot; every number, n, grade and level next to a refId in Default, the decision table, the sweat-test section, Before/After and Red flags matches its entry.
Verification 2026-10-01: Level B is honest — the safety rule is an A- consensus graded mostly 1C plus one B+ cohort; volumes and cut-offs are labelled practice. No LEVEL-OVERALL.
Verification 2026-10-01: second title fix, not in the title pair (one pair allowed): 'nor most cramps' -> 'and is not shown to prevent cramps'.
Verification 2026-10-01: disclosed, not flagged — the masters row (plan, per REF-748) departs from the thirst rule (REF-776), and the ultra stand's 450-750 mL/h (REF-528) conflicts with thirst; both are stated and resolved as labelled inference, consistent with SYNTH-65, SYNTH-63, SYNTH-57 and SYNTH-02.
Verification 2026-10-01: 'never drink more than you lose' (during exercise) and 'after a >2% deficit, 125-150% of the loss' (REF-748, after exercise) are not in conflict but sit close; a reader could confuse them.
2026-10-01: the long-event row now says which row wins for a hot marathon, Ironman or ultra (the hot-race row, still capped at the weighed loss), so the frameworks that point here (SYNTH-64, SYNTH-65, SYNTH-57, SYNTH-06) read one rule.
Revision 2026-10-26: REF-1194 (Mougin 2026, C+) added to the ultra-conflict paragraph as an observed case (0.87 L/h, 18.5 g sodium, −4.3% body mass at up to 40 °C); the resolution and level unchanged.